Laboratories
The Genomics and Development of Childhood Cancers lab (https://institut-curie.org/team/saulnier), headed by Dr. Olivier Saulnier is looking for a motivated bioinformatician on cancer/single-cell genomics.
We are located in the heart of Paris at Institut Curie, one of the world's leading institutions in cancer research. It represents an excellent and international environment with interdisciplinary expertise and high-quality technological platforms.
Missions
Our lab aims to better understand the development origins of childhood brain cancers. The project will involve multi-omics characterization of human fetal tissue and childhood brain tumors using single-cell and spatial approaches.
Key publications
1/ Saulnier*, Zagozewski*, Liang*, Hendrikse*, et al., A Group 3 medulloblastoma stem cell program is maintained by OTX2-mediated alternative splicing. Nature Cell Biology. 2024
2/ Visvanathan*, Saulnier*, Chuan*, et al., Early Rhombic Lip Protogenin+ve Stem Cells in a Human Specific Neurovascular Niche Initiate and Maintain Group 3 Medulloblastoma. Cell 2024
3/ Hendrikse*, Haldipur*, Saulnier*, et al., Failure of human rhombic lip differentiation underlies medulloblastoma formation. Nature. 2022
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Bioinformaticien – Ingénieur (F/H) in Paris employeur : Institut Curie
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