Organisation/Company Grenoble INP - Institute of Engineering Department Engineering Research Field Engineering » Materials engineering Researcher Profile First Stage Researcher (R1) Positions Postdoc Positions Application Deadline 19 Nov 2026 - 20:00 (Europe/Paris) Country France Type of Contract Temporary Job Status Full-time Offer Starting Date 1 Feb 2027 Is the job funded through the EU Research Framework Programme? Not funded by a EU programme Is the Job related to staff position within a Research Infrastructure? No
Offer Description
The BAM project — 3D biomimetic adaptable materials for life sciences — aims to validate 3D polymer scaffolds with independently adjustable mechanical properties and biochemical composition.
These scaffolds reproduce selected features of the extracellular matrix. The project will assess whether BAM supports cellular responses closer to in vivo reference data than conventional 2D plastic cultures. The resulting proof-of-concept data will support technology development and future applications in life sciences and drug screening.
Under the scientific supervision of Elisa Migliorini, the researcher will carry out biological validation of BAM, primarily using neuroblastoma and hereditary multiple exostoses models, in collaboration with the project team and specialist biological partners.
Prepare and functionalise BAM scaffolds, select stiffness and biochemical conditions suited to each model, and document experimental protocols.
Conduct cell culture experiments on 3D scaffolds and 2D controls; assess viability, morphology and differentiation using immunofluorescence and quantitative imaging.
Select relevant conditions for transcriptomic validation, prepare samples for bulk and/or single-cell RNA sequencing, and contribute to data interpretation with the project specialists.
Assess reproducibility, maintain traceable experimental records, and prepare datasets, protocols and reports for project monitoring and technology transfer
Requirements
Research Field Engineering » Materials engineering Education Level PhD or equivalent
Skills/Qualifications
PhD in surface chemistry, biomaterials or bioengineering. Experience at the materials–cell interface is needed.
Core competencies:
- cell culture, immunostaining, fluorescence microscopy and quantitative image analysis
- ability to design comparative experiments and analyse data
- knowledge of surface functionalisation, extracellular matrix biology, 3D culture and transcriptomics
- scientific rigour and autonomy
- organisation, interdisciplinary teamwork
- good written and spoken scientific English
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Researcher in biomaterials and biological validation of 3D cell culture systems - SYMMES employeur : Grenoble INP - Institute of Engineering
Grenoble INP - Institute of Engineering est un employeur de choix, offrant un environnement de recherche dynamique et collaboratif au sein du laboratoire PHELIQS. Les employés bénéficient d'opportunités de croissance professionnelle grâce à des projets innovants dans le domaine des technologies quantiques, tout en travaillant avec des experts de renommée mondiale. Situé à Grenoble, un pôle technologique en pleine expansion, le laboratoire favorise une culture de l'excellence et de la curiosité scientifique, idéale pour ceux qui cherchent à contribuer à des avancées significatives dans la physique des matériaux et l'ingénierie nanométrique.
Coordonnées :
Équipe de recrutement de Grenoble INP - Institute of Engineering
