Organisation/Company CNRS Department Laboratoire de Biologie Structurale de la Cellule Research Field Chemistry Physics » Biophysics Biological sciences » Biological engineering Researcher Profile Recognised Researcher (R2) Application Deadline 16 Nov 2026 - 23:59 (UTC) Country France Type of Contract Temporary Job Status Full-time Hours Per Week 35 Offer Starting Date 1 Feb 2027 Is the job funded through the EU Research Framework Programme? Not funded by a EU programme Is the Job related to staff position within a Research Infrastructure? No
Offer Description
Develop and experimentally characterise RNA-peptide systems capable of self-organisation, molecular reactions and differential persistence under environmental constraints, within the MICROFLUIDICS targeted project of the PEPR Origins programme.
- Design, produce and purify functional RNAs and associated peptides.
- Form and characterise RNA-peptide coacervates by microscopy, biophysical measurements and quantitative analyses.
- Study ligation, recombination, amplification or templating reactions within the compartments.
- Measure the effects of salinity, dilution and dehydration-rehydration cycles on the stability and reorganisation of coacervates.
- Analyse data, document results and contribute to reports, publications and meetings of the PEPR Origins programme.
The position is attached to the Synthetic Biosystems team (head: Philippe Nghe) of the Laboratory of Structural Biology of the Cell (BIOC, UMR 7654, CNRS - Ecole polytechnique). The team builds molecular systems endowed with Darwinian properties to study the emergence of evolution. The MICROFLUIDICS targeted project (WP4.2) of the PEPR Origins programme brings together BIOC, ICMCB (Bordeaux), PIIM (Marseille) and I2M (Bordeaux).
Research Field Biological sciences » Biological engineering Years of Research Experience 1 - 4
Additional Information
Eligibility criteria
- RNA biochemistry and molecular biology; RNA-peptide interactions; liquid-liquid phase separation and coacervates; kinetics and thermodynamics of molecular interactions.
- Nucleic acid preparation and purification, electrophoresis, ribozyme assays, fluorescence microscopy and image analysis, sequencing and quantitative data processing.
- Experimental rigour, autonomy, teamwork, scientific writing in English.
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Postdoctoral researcher (M/F) in RNA biochemistry and RNA-peptide protocells employeur : CNRS
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